Aciphex - with you If you take this medicine for any other condition, you may take it with or without food. Vitamin B12 needs a Acpihex called intrinsic factor in order to be absorbed from the digestive tract. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other Aciphex clinical experience Aciphx not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. According to Lexi-Comp, there are adverse effects reported with Pariet that include diarrhea, nausea, and in rare cases fever. Patients need to be monitored 7. So, after years of PPI use, it may be necessary to take a calcium supplement. As a result of these problems, FDA in December updated Aciphex warning labels to include information about acute interstitial nephritis. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. There have been well-documented reports of individuals with a history of penicillin hypersensitivity reactions that have experienced severe hypersensitivity reactions when treated with a cephalosporin. Talk to your doctor about the risk of taking rabeprazole. Journal of Labelled Compounds and Radiopharmaceuticals. Aciphex your doctor about all Aciphez your medical conditions, including if you: have any liver problems have any allergies Aciphdx pregnant or planning to become pregnant. Pseudomembranous colitis has been reported with nearly all antibacterial agents, including clarithromycin and amoxicillin, and may range in severity from mild to life threatening. See Biaxin entry for more information on clarithromycin. In the U. Retrieved 10 January These metabolites were not observed to have significant antisecretory activity. Retrieved 9 October The percentages of patients with endoscopic healing at two and four weeks are presented below:. Many drugs can interact with rabeprazole, especially:. Rabeprazolesold under the brand name Pariet among others, is a medication that decreases stomach acid. A few patients may require additional therapy to achieve healing. ACIPHEX is contraindicated in patients with known hypersensitivity to rabeprazole, substituted benzimidazoles, or to any component of the formulation. Expert Opinion on Drug Safety. Studies in juvenile and young adult rats and dogs were performed. Browse Drugs and Medicines. ACIPHEX produced satisfactory inhibition of gastric acid secretion in all patients and complete resolution of signs and symptoms of Aciphexx disease where present. The group median values stayed within the normal range. The lethal overdose syndrome in animals is characterized by convulsion and coma. How likely would you be Aciphexx recommend Aciphex to a friend? See full prescribing information for a list of clinically important drug interactions 7. Aciphes U. In vitro incubations employing human liver microsomes indicated that rabeprazole inhibited cyclosporine metabolism with an IC 50 of 62 micromolar, a concentration that is over 50 times higher than the C max in healthy volunteers following 14 days of dosing with 20 mg of rabeprazole. Skip to Content. Aciphex also comes in the form of Aciphex Sprinkle - 5 mg and 10 mg delayed-release capsules - for children. Robin ACIPHEX is indicated for short-term up to four weeks treatment in the healing and symptomatic relief of duodenal ulcers. AcipHex rabeprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. It is also used in adults to promote healing of duodenal ulcers or erosive esophagitis damage to your esophagus caused by stomach acid. Do not save it for later use. ACIPHEX delayed-release tablets are indicated for short-term up to four weeks treatment in the healing and symptomatic relief of duodenal ulcers. Tell your doctor about all of your medical conditions, including if you:. ACIPHEX Aciiphex prevented recurrence of gastric hypersecretion and manifestations of acid-peptic disease in all patients. Retrieved 10 January There is no appreciable accumulation when Afiphex of 10 Acjphex to 40 mg are administered every 24 hours; the pharmacokinetics of rabeprazole are not altered by multiple dosing. A: Aciphex rabeprazole belongs to a class of drugs called proton pump inhibitors PPIs that decreases the amount of acid Aciphex in the stomach. Rabeprazole Acihpex is known chemically as 2-[[[4- 3-methoxypropoxy methylpyridinyl]-methyl]sulfinyl]-1 Acuphex benzimidazole sodium salt. A selective pattern C—see below for a discussion of cross-reactivity patterns type I hypersensitivity reaction to rabeprazole resulting in anaphylaxis has been reported, as well as several whole group hypersentivities. Rabeprazole is classified as a substituted benzimidazolelike omeprazolelansoprazoleand pantoprazole. About About Drugs. In comparison, rabeprazole is not as significantly metabolized by this enzyme compared to other medications in the same class, like omeprazole. Tell your doctor if you are pregnant or plan to become pregnant. Intervention: Monitor digoxin concentrations. GERD happens when acid in your stomach backs up into the tube esophagus that connects your mouth to your stomach. A significant portion of rabeprazole is metabolized via systemic nonenzymatic reduction to a thioether compound. Do not take 2 doses at the same time. In patients with endoscopically defined duodenal ulcers treated for up to four weeks, ACIPHEX was comparable to omeprazole in producing healing of duodenal ulcers. Rabeprazole has been sold in a number of brand names: .
Aciphex is an antiulcer medication which inhibits a proton pump (PPIs) and blocks the production of acid by the stomach. Biochemically it blocks the (H+,K+)-ATPase enzyme system hereby inhibiting the final stage of hydrochloric acid production. After peroral intake of Aciphex antisecretorial effect is reached during one hour and is maximal in 2-4 hours. This medication is used to treat ulcers in stomach, Zollinger-Ellison syndrome, gastroesophageal reflux disease, to eradicate Helicobacter pylori in patients with ulcers in stomach or chronic gastritis.
Dosage and directions
Dosage should be administered by your doctor depending on your condition. Usually in patients with an acute duodenal ulcer and c it is recommended to take 1 tab (20 mg) in morning one time a day during 4-6 weeks. When treating H. pylori infection, Aciphex may be needed for only a week. Follow all recommendations of your doctor and do not take this drug in larger amounts than it was prescribed to you. Tablets should be swallowed whole. Do not crush, split or chew them. Take Aciphex with or without meals with a big glass of water since food has little effect on its absorption.
Notify your doctor if you have a severe liver disease, cancer of stomach before to take this drug. Use of Aciphex in children is not recommended. It is not expected to be harmful to an unborn baby, though inform your doctor if you are pregnant or breastfeeding. Some conditions are treated with a combination of Aciphex and antibiotics, so to achieve maximal effect from treatment, use all of your medications as directed by your doctor.
Pregnancy, breastfeeding, hypersensitivity to Aciphex or a substituted benzimidazoles: omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Aciphex), and esomeprazole (Nexium).
Possible side effect
Together with symptoms of allergy (hives, rash, swelling of tongue and face) such side effects may occur: headache, dizziness, dry mouth, upset stomach or diarrhea, constipation, insomnia, nervousness, rash, or itching. Contact your doctor for help if any of the listed side effects is severe or persistent.
Co-administration with the medications which absorption depends on acidity of the stomach causes interaction of medications. Aciphex and other PPIs reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin) causing reduction of effectiveness of the former and increase of toxicity of the latter.
If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.
Symptoms of Aciphex overdose are unknown. If you consider that you took too much of the drug seek emergency medical attention.
Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.
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