Allopurinol
Generic Allopurinol
Allopurinol is an arthrifuge which inhibits xanthine oxidase and prevents formation of uric acid, from xanthine and hypoxanthine.
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Allopurinol $68.00
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These are not all the side effects of allopurinol. About About Drugs. What other information should I know? Will it affect my contraception? It is important to make sure your child drinks plenty of liquid each day 4 or 5 large glasses of water. The most common side effects are feeling or being sick. You may have gout attacks more often when you first start taking allopurinol. What is allopurinol and how is it used? If you think someone else may have taken the medicine by accident, contact your doctor straight away. This can happen months or years after treatment is started. Azathioprine can used for treating conditions such as: rheumatoid arthritis roo-ma-toy-d arth-ri-tus Crohn's disease kro-wnz diz-eez ulcerative colitis ul-ser-ay-tive col-eye-tis lupus loo-pus dermatomyositis der-mer-toe-my-oh-sigh-tus hepatitis hep-er-tie-tus vasculitis vask-you-lie-tis. A high uric acid level can cause gout or gouty arthritis joint pain and inflammation. This content does not have an Arabic version. Explore now. However, alcohol increases the amount of urate in the blood. Drug information provided by: IBM Micromedex. Check with your doctor or pharmacist before giving any other medicines to your child. However, drinking alcohol can trigger an attack of Allopurinol. Your reactions could be impaired. Hidden categories: Template:drugs. Please review our privacy policy. First, its dosing is complex. Allopurinol is a xanthine oxidase inhibitor that works by decreasing the uric acid produced by the body. IUPAC name. These effects should wear off as your child gets used to the medicine. National Center for Biotechnology InformationU. What side effects can this medication cause? Explore now. Choose a degree. Gout Symptoms, Diagnosis and Treatment. The most common Allopurinkl effects are feeling or being sick. Allopurinol pronounced as al oh pure' i nole. Less common side effects, in 1 to 10 percent of the population, include drowsiness, chills, fever, alopecia, nausea, vomiting, diarrhea, abdominal pain, gastritis, dyspepsia, and abnormal liver tests. Retrieved 8 November Gout causes attacks of painful inflammation in one or more of your joints.
Common use

Allopurinol is an arthrifuge which inhibits xanthine oxidase and prevents formation of uric acid, from xanthine and hypoxanthine. Reduces the concentration of uric acid and its salts in body fluids, promotes the dissolution of existing urate deposits and prevents their formation in tissues and kidneys. The medication is used to treat diseases accompanied by hyperuricemia: gout (primary and secondary), nephrolithiasis (forming of kidney stones from urates); hyperuricemia (abnormally high level of uric acid in blood, both primary and secondary), which results in diseases involving enhanced dissolution of nucleoproteins and elevated levels of uric acid in the blood, including at various forms of leukemias, and also for treatment of some other conditions.



Dosage and direction

The dose of 100-800 mg a day may be prescribed depending on the condition. Initial dose of 100 mg can be increased gradually. Patients with acute gout and tophi (uric acid crystals in the tissues mostly around joints) should be treated with 300-400 mg of Allopuionol daily. Doses over 300 mg should be divided in two or more intakes. Take medication with food to avoid irritation of the stomach. Do not take large doses of vitamin C. Drink plenty of water to avoid formation of kidney stones. Limit consummation of alcoholic beverages and purine-rich foods such as sweetbreads, sardines, anchovies, kidneys, liver, and lentils.



Precautions

Allopurinol should be taken over a period of several months so your symptoms start to reduce. Regular intake is important even no immediate effect is noticed. You may experience acute attacks of gout more often at the beginning of treatment with Allopurinol even after normal uric acid levels are reached. The attacks will become shorter and less acute as the therapy continues. At any sign of allergic reaction stop taking the medication and consult your doctor as development of serious skin disease, irreversible damage to the liver, or generalized inflammation of a blood or lymph vessel is possible in some individuals. Inform your doctor if you have diabetes or kidney dysfunction before to take Allopurinol as correction of your dose is needed.



Contraindications

Allopurinol cannot be used in patients with hypersensitivity to the medication, in individuals with a hepatic or renal disorders, primary hemochromatosis, asymptomatic hyperuricemia, acute gout, pregnancy, lactation. The medication cannot be prescribed to children under 14 years of age unless the patients are treated for leukemia, malignant tumors and enzymatic disorders. C care. Renal failure, heart failure, diabetes mellitus, hypertension.



Possible side effect

The most common adverse reactions are diarrhea, nausea, allergy (rash, itching), and drowsiness. Stop taking the medication at first signs of rash, painful or bloody urination, eye irritation, or facial swelling, because these can be signs of a severe allergic reaction requiring immediate treatment. In rare cases Allopurinol can cause damage to nerve, kidney, and bone marrow as well as be a reason to a serious and even fatal allergic liver toxicity. In patients with liver toxicity appetite loss and itching may witness about it. The risk increases in patients with kidney impairment.



Drug interaction

The dose of oral mercaptopurine (Purinethol) and azathioprine (Imuran) should be reduced as Allopurinol increases their blood levels. Risk of skin rash increases in patients taking Allopurinol with penicillins.



Missed dose

Take the missed dose as soon as you remember unless it is almost time of your next dose. If it is almost time of your next dose just skip it and return to your regular scheme. Do not exceed the recommended dose.



Overdose

In case of suspected overdose seek for immediate medical attention. No specific information is available about Allopurinol overdose.



Storage

Store at room temperature, below 25 C (77 F) and out of reach and children and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis.All specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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