DDAVP - sorry, that Release into plasma as a large molecule, followed by breakdown into varying sizes of multimeric molecules by a plasma protease. Use the medicine exactly as directed. Your doctor may need to change the doses of your medications or monitor you carefully DDAVVP side effects. If sodium levels become too low hyponatremia — either DDAAVP a result of increased water take-up or reduced salt levels — a person may have seizures and, in extreme cases, may die. If you become pregnant while taking desmopressin, call your doctor. We are the EMCrit Projecta team of independent medical bloggers and podcasters joined together by our common love of cutting-edge care, iconoclastic ramblings, and FOAM. The Journal of Endocrinology. Actual Primary Completion Date :. Other bleeding disorders Various acquired or inherited disorders of bleeding have been documented to respond to desmopressin. Maximal dose response occurred at 0. Study Description. These patients are classified into the category of mild or moderate haemophilia, and may fortunately respond to desmopressin. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Your doctor may start you on a low dose of desmopressin and gradually increase your dose. Desmopressin may cause other side effects. Desmopressin pronounced as des moe press' in. This formulation is administered subcutaneously or by direct intravenous injection. The skin bleeding time may be helpful in following these patients. Scott H. DDAVP Class. Drinking too much fluid while you are taking desmopressin can be dangerous, so your doctor will probably tell you to stop taking desmopressin temporarily. View All. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. What special dietary instructions should I follow? In addition, it has little effect on blood pressurewhile vasopressin may cause arterial hypertension. Detailed Description:.
Generic DDAVP nasal spray used to prevent or control the frequent urination and loss of water caused by diabetes insipidus characterized by frequent urination, which can disrupt sleep and sometimes to cause bed-wetting. Active substance of the drug is desmopressin acetate.
Dosage and direction
The usual dose is from 1 to 4 sprays daily (0.1 to 0.4 ml), dosage depends on the medical condition and response to DDAVP. In children between 3 months to 12 years of age the recommended dose is 0.05- 0.3 ml daily, taken as a single dose or divided into 2 doses. Do not use the medication more frequently than prescribed. Avoid drinking too much liquid while on DDAVP. Never swallow the medication or let the liquid run into your mouth.
Cautiousness is required in the patients with cystic fibrosis, any condition in which there is fluid and electrolyte imbalance, high blood pressure and/or coronary artery disease. In case of continued nasal bleeding while using DDAVP contact your doctor.
This medicine is contraindicated in the patients with hypersensitivity to the components of DDAVP.
Possible side effect
High doses may result in nausea, headache, mild abdominal cramps, irritation of the nose, stuffy nose, or flushing. Other adverse reactions may include: conjunctivitis (pinkeye), depression, dizziness, inability to produce tears, nostril pain, rash, swelling around the eyes, weakness, stomach or intestinal upset, fluid retention and swelling, agitation, chest pain, chills, dizziness, indigestion, insomnia, itchy or light-sensitive eyes, inflammation of the penis, pain, sleepiness, vomiting, warm feeling, pounding heartbeat, rapid heartbeat.
Inform your doctor if you are currently taking any drug used to increase blood pressure (dopamine, epinephrine, ephedrine, levophed), Clofibrate, Glyburide, Epinephrine, carbamazepine, chlorpropamide, demeclocycline, water pills (diuretics). Concomitant use of alcoholic beverages and DDAVP increases urination.
If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.
Any drug taken in excess may be dangerous. If you suspect an overdose, seek immediate medical help. Symptoms of DDAVP overdose include abdominal cramps, headache, flushing, or nausea.
Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.
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