DDAVP
Generic DDAVP (Desmopressin)
Generic DDAVP is used to prevent or control the frequent urination and loss of water caused by diabetes insipidus.
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0.1mg
30pills
DDAVP $184.79
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0.1mg
60pills
DDAVP $302.39
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0.1mg
90pills
DDAVP $419.99
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0.1mg
120pills
DDAVP $509.24
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10mcg
1spray
DDAVP $116.00
$101.84
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10mcg
2sprays
DDAVP $193.00
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10mcg
3sprays
DDAVP $268.00
$234.14
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10mcg
4sprays
DDAVP $328.00
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10mcg
8sprays
DDAVP $595.00
$520.79
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DDAVP - sorry, that

Release into plasma as a large molecule, followed by breakdown into varying sizes of multimeric molecules by a plasma protease. Use the medicine exactly as directed. Your doctor may need to change the doses of your medications or monitor you carefully DDAVVP side effects. If sodium levels become too low hyponatremia — either DDAAVP a result of increased water take-up or reduced salt levels — a person may have seizures and, in extreme cases, may die. If you become pregnant while taking desmopressin, call your doctor. We are the EMCrit Projecta team of independent medical bloggers and podcasters joined together by our common love of cutting-edge care, iconoclastic ramblings, and FOAM. The Journal of Endocrinology. Actual Primary Completion Date :. Other bleeding disorders Various acquired or inherited disorders of bleeding have been documented to respond to desmopressin. Maximal dose response occurred at 0. Study Description. These patients are classified into the category of mild or moderate haemophilia, and may fortunately respond to desmopressin. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Your doctor may start you on a low dose of desmopressin and gradually increase your dose. Desmopressin may cause other side effects. Desmopressin pronounced as des moe press' in. This formulation is administered subcutaneously or by direct intravenous injection. The skin bleeding time may be helpful in following these patients. Scott H. DDAVP Class. Drinking too much fluid while you are taking desmopressin can be dangerous, so your doctor will probably tell you to stop taking desmopressin temporarily. View All. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. What special dietary instructions should I follow? In addition, it has little effect on blood pressurewhile vasopressin may cause arterial hypertension. Detailed Description:.

DDAVP - words

Factor IX and FVIII work together to activate DDAPV X, so artificially increasing the levels of one factor is not expected DDAPV compensate for the lack of the other. Selection criteria:. What's Your Job. A rare but DDAAVP side effect in patients receiving desmopressin is the occurrence of arterial thrombotic events, such as stroke or acute myocardial infarction. Unfortunately, these patients do not benefit from administration of desmopressin, because increases in plasma levels of VWF alone without its precious cargo, the FVIII molecule, will not translate into a haemostatic effect. Ginsburg D. Desmopressin is also used to control bed-wetting. Desmopressin has revolutionised the treatment of bleeding disorders since its introduction to haematology in If a patient with hypovolemic hyponatremia is volume resuscitated, at a certain point perfusion improves and this shuts off vasopressin figures below. Desmopressin is in a class of medications called hormones. Although this example focuses on hypovolemic hyponatremia, overcorrection will also occur after treatment of any reversible cause of hyponatremia e. Desmopressin is not approved to treat bed-wetting in a child younger than 6 years old. You are viewing BNF. Subscribe to Drugs. Keep all appointments with your doctor and the laboratory. A recent systematic review of DDAVP use concluded that the proactive strategy was associated with the lowest incidence of over-correction. Surprisingly, a recent NEJM review article supported the use of vaptans, accepting this expert panel over the European consensus guidelines. Symptoms of overdose may include the following: confusion drowsiness headache difficulty urinating sudden weight gain. Desmopressin side effects in more detail. The gene for VWF is located on chromosome Phase 2. It was only years later, well into the late 20th century, that it was appreciated that the disease originated from a quantitative or qualitative deficiency of a plasma protein of high importance in the normal haemostatic mechanism. DDAVP this study. Understanding the physiology of sodium over-correction allows us to anticipate this, but it is still unclear when it will occur. Various acquired or inherited disorders of bleeding have been documented to respond to desmopressin. Use with caution; antidiuretic effect may be reduced. In other projects Wikimedia Commons. It does not come from human plasma and it carries no risk of infection. Dose groups: Group 1: 0. DDAVP is a drug used to effectively increase the concentration of factor VIII in the blood and to increase the clumping together of platelets to stop bleeding. This approach is very innovative but limited to hypovolemic cases only. Please review our privacy policy. DDAVP therapeutic trial can be undertaken for each individual woman to gauge the clinical response, as DDDAVP guide for future plan of action. The response to DDAVP of factor VIII activity and plasminogen activator is dose-related, with maximal plasma levels of to percent of initial concentrations obtained after infusion of 0. Desmopressin side effects in more detail. European Journal of Clinical Investigation. There are, however, no adequate and well controlled studies in pregnant women. Received Aug 5; Accepted Sep
Common use

Generic DDAVP nasal spray used to prevent or control the frequent urination and loss of water caused by diabetes insipidus characterized by frequent urination, which can disrupt sleep and sometimes to cause bed-wetting. Active substance of the drug is desmopressin acetate.



Dosage and direction

The usual dose is from 1 to 4 sprays daily (0.1 to 0.4 ml), dosage depends on the medical condition and response to DDAVP. In children between 3 months to 12 years of age the recommended dose is 0.05- 0.3 ml daily, taken as a single dose or divided into 2 doses. Do not use the medication more frequently than prescribed. Avoid drinking too much liquid while on DDAVP. Never swallow the medication or let the liquid run into your mouth.



Precautions

Cautiousness is required in the patients with cystic fibrosis, any condition in which there is fluid and electrolyte imbalance, high blood pressure and/or coronary artery disease. In case of continued nasal bleeding while using DDAVP contact your doctor.



Contraindications

This medicine is contraindicated in the patients with hypersensitivity to the components of DDAVP.



Possible side effect

High doses may result in nausea, headache, mild abdominal cramps, irritation of the nose, stuffy nose, or flushing. Other adverse reactions may include: conjunctivitis (pinkeye), depression, dizziness, inability to produce tears, nostril pain, rash, swelling around the eyes, weakness, stomach or intestinal upset, fluid retention and swelling, agitation, chest pain, chills, dizziness, indigestion, insomnia, itchy or light-sensitive eyes, inflammation of the penis, pain, sleepiness, vomiting, warm feeling, pounding heartbeat, rapid heartbeat.



Drug interaction

Inform your doctor if you are currently taking any drug used to increase blood pressure (dopamine, epinephrine, ephedrine, levophed), Clofibrate, Glyburide, Epinephrine, carbamazepine, chlorpropamide, demeclocycline, water pills (diuretics). Concomitant use of alcoholic beverages and DDAVP increases urination.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Any drug taken in excess may be dangerous. If you suspect an overdose, seek immediate medical help. Symptoms of DDAVP overdose include abdominal cramps, headache, flushing, or nausea.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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