Dilantin - consider Phenytoin may cause other side effects. L-type-selective : Bay K The extended release capsule should not be opened, as the entire dose would be delivered, so make sure to swallow it whole. Cochrane Database of Systematic Reviews. Clinical Trials Information. Building a Diverse Workforce. Dilantin Interactions. Geneva: World Health Organization. Previous NCI Directors. There is no good evidence that phenytoin is a human carcinogen. Sometimes they are serious, most of the time they are not. I asked them if the new Dilantin contained Aspartame. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. Your doctor may need to change the doses of your medications or monitor you more carefully for side effects. Metastatic Cancer Research. Archived PDF from the original on 19 April Cochrane Database of Systematic Reviews. Follow all directions given to you by your doctor carefully. You can get in touch with a poison control center at. You may also need a blood test when switching from one form of phenytoin to Dilantin. See here instead. Generic iDlantin usually cost less than the brand-name version. Sigma receptor modulators. Visit your Dilantni regularly. Sometimes it is not safe to use certain medications at the same time. I am now close to running out of the old Dilantin. Blockers Glibenclamide Lonidamine Piretanide. Your doctor will check your progress and may want to take some tests from time to time. The primary site of action appears to be the motor cortex, where the spreading of seizure activity is inhibited. Glibenclamide Lonidamine Piretanide. This reduces how often you have seizures.
Dilantin - even more All I know is, that the new dilantin contains something that give me problems. Skip to Content. Burlington, MA. The drug is Dilanhin a class of medications known as anticonvulsants. Dilantin can pass into breast milk and may harm a breastfeeding baby. Do not start or stop taking Dilantin without your doctor's advice if you are Dilantin. Phenytoin is primarily metabolized to its inactive form by Dilwntin enzyme CYP2C9. Sponsorship Request Sponsorship Request If you are human, leave this field blank. Aspartame can cause seziures in people who don't have epilepsy. In some cases, they may not be available in every strength or form as the brand-name drug. Beth Isaac, PharmD. Retrieved Aug 22, This puts you at risk for toxicity and side effects. Use the dosing syringe provided, or use a medicine dose-measuring device not a kitchen spoon. Drinking soda and other sources of liquid sugar is highly fattening and unhealthy. Earlier in a study, the Mayo Clinic found that of patients receiving Dilantin injections, 9 about 5. Follow your doctor's dosing instructions very carefully. Taking these anti-seizure drugs with phenytoin can increase the level of phenytoin in your body. The two halves of the old one were sealed with a band, and the new one is self-locking.
Dilantin is anti-seizure medication described as an effective drug which reduces electrical conductance among brain cells by stabilizing the inactive state of voltage gated sodium channels. This medication is used to treat epilepsy (seizures), to prevent post-traumatic epilepsy and epilepsy caused by neurosurgery, ventricular arrhythmias, including intoxication with cardiac glycosides, some forms of Meniere's syndrome, trigeminal neuralgia and many other conditions.
Dosage and directions
Dose of Dilantin in patients treated for non-epileptic disease should be several times lower than in ones with epilepsy. Your dosage should be prescribed by your doctor. A recommended daily dose to treat epileptic seizures is 5 mg per kilo in adults and 4-7 mg per kilo in children. The daily dose should be divided for 1-2 intakes. If to take the medication with food it may reduce its side effects. Correction of the dose is needed in elderly patients, debilitated persons, and patients with certain kidney or liver diseases. Do not use Dilantin suspension at the same time as tube feedings. Do not stop taking this drug without your doctor's permission even if you feel fine as you may have increase in seizures. Do not chew, crush, break, open an extended-release capsule; swallow the whole pill. Shake the suspension before to use it and measure it with a special spoon.
Before to take Dilantin inform your doctor if you have liver or kidney disorder, vitamin D deficiency, diabetes, porphyria, pregnant or plan to become pregnant, breastfeeding. Serious skin reaction to Dilantin may rarely develop in patients of Asian ancestor. This medication can make contraception pharmaceuticals less effective. This drug may change your ability to drive or operate machinery which requires high concentration of attention. Do not take with antacids.
Dilantin is prohibited in patients with liver and kidneys diseases, leukopenia, heart failure, cachexia, porphyria and in patients concomitantly treated with isoniazid, teturamom, aspirin. Cautiousness should be exercised in pregnant or breastfeeding patients (increased risk of malformations and birth defects), ones sick with diabetes.
Possible side effect
Adverse side effects may appear during treatment with Dilantin: dizziness, agitation, tremor, ataxia, nystagmus (involuntary eyes movements), fever, nausea, vomiting, changes in connective tissue (coarsening of facial features, Dupuytren's contracture), allergic reaction (rash, itching). Prolonged use of the medication in patients and especially in children may causes dyspepsia, gingival hyperplasia (overgrowth of the gums), osteopathy, hypocalcemia, megaloblastic anemia. In rare cases lymphadenopathy and hirsutism (excessive and increased hair growth) may appear. Lymph nodes may sometimes painfully swell up. Level of glucose may rise also so it should be used cautiously in patients with diabetes. Weakness of the bones stipulated by interference of Dilantin into the synthesis of vitamin D may appear. Risk of suicidal behavior in patients treated with Dilantin increases. In case of any serious side effects listed above and also ones of allergy seek for immediate medical help.
Dilantin increases effects of coumarin anticoagulant drugs, while the anticoagulants in their turn increase blood levels of Dilantin which may aggravate risk of toxicity and hemorrhagic complications. Inform your doctor if you are taking digoxin, carbamazepine, clonazepam, corticosteroids (prednisone), cyclosporine, disopyramide, doxycycline, estrogens, felodipine, levodopa, lidocaine, methadone, mexiletine, oral contraceptives, paroxetine, quinidine, tacrolimus, theophylline, phenobarbital, and warfarin as they may decrease blood levels of Dilantin.
Tricyclic antidepressants [Amitriptyline (Elavil, Endep), Desipramine (Norpramin, Pertofrane), Amoxapine (Asendin), Clomipramine (Anafranil), Imipramine (Tofranil), Nortriptyline (Pamelor, Aventyl), Doxepin (Adapin, Sinequan), Protriptyline (Vivactil), Trimipramine (Surmontil)] in large doses diminish a convulsive threshold and in small doses increase it, some of them are able to slow down metabolism of Dilantin and increase its toxicity hereby. Isonicotinic acid, certain antibiotics (levomitsetin), sulfonamides, aminasine are able to increase toxicity of Dilantin.
Dilantin increases hypotention effects of diuretics and other anti-hypertension medications, strengthens action of anapryline and antiarrhythmic medications, thyroid hormone replacement drugs. Dilantin decreases activity of medications for diabetes, affects metabolism of corticosteroids and tetracycline (Vibramycin), influences absorption of diuretics (Furocemide). Dilantin may increase indices of bilirubin, cholesterol, glucose, alkaline phosphatase, liver transaminases in blood tests.
If you missed a dose take it as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule.
Large doses of Dilantin cause ataxia, nystagmus, diplopia (double vision), extrapyramidal disorder, hyperkinesia (muscular activity), sensory neuropathy. High concentration of Dilantin (more than 50 mg/l) in rare cases may cause aggravation of attacks, sopor (abnormally deep sleep) and coma. Large doses of the medication increase blood levels of glucose in patients who are not sick with diabetes. Blood levels of Dilantin over 20 mg/l in children may lead to acute toxicity: nystagmus, ataxia, mental disorders, joint pain, and in more severe cases bradycardia, ventricular fibrillation, atrial flutter, asystole, and coma. If you suppose that Dilantin was overdosed seek for immediate medical help.
Store tablets, capsules, and suspension of Dilantin at room temperature, 15-30 C (59-86 F).
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.