Hydroxycarbamidealso known as hydroxyureais a medication used in sickle-cell diseasechronic myelogenous leukemiacervical cancerand polycythemia vera. Everyday Health Drugs Antimetabolites Hydroxyurea. Keep all appointments with your doctor and laboratory. Ask your pharmacist for a list of the ingredients. Onset: hours Nadir: 10 days Recovery: within days of stopping therapy reversal of white blood count occurs rapidly, but the platelet count may take days to recover. Contact your health care provider within 24 hours of noticing any of the following:. This medicine may raise the chance of getting cancer. Ribonucleotide reductase inhibitor Hydroxycarbamide. Call your doctor if you have any unusual problems while taking this medication. Last Reviewed: August 7, Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:. Your blood will need to be tested often. Do not flush down the toilet or throw in the trash. Other brands: DroxiaSiklosMylocel. About Cancer generously supported by Dangoor Education since David
Hydrea - apologise Other drugs may affect Hydrea, including prescription and over-the-counter medicines, vitaminsand herbal products. Swallow the pill whole with a glass of water. Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:. You may not be able to become pregnant or father a child after treatment with this drug. This can lead to very bad and sometimes deadly bleeding problems or infections. Tumor Lysis Syndrome: If there are a large amount of tumor cells in your body prior to treatment, you are at risk for tumor lysis syndrome. Dihydrofolate reductase inhibitor Aminopterin Methotrexate Pemetrexed Pralatrexate Thymidylate synthase inhibitor Raltitrexed Pemetrexed. Ask your oncology team where to return any unused medication for disposal. Some patients may develop a rash or very dry skin. Avoid the sun between pm, when it is strongest. Different drugs may affect different parts of the body. Tell Hydrea doctor at once if you develop signs of infection. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. If you are a female, you should use effective birth control while taking hydroxyurea and for at least 6 months after stopping your treatment. You should not breast-feed while you are taking hydroxyurea. Be sure to mention any of the following: certain medications for HIV human immunodeficiency virus such as didanosine Videx and stavudine Zerit and interferon Actimmune, Avonex, Betaseron, Infergen, Intron A, others. Questions about cancer? Hydroxyurea slide 5 of 10, Hydroxyurea. Where can I get more information? Hydroxyurea is used to treat chronic myeloid leukemia, ovarian cancer, and certain types of skin cancer squamous cell cancer of the head and neck. Skip to Content. About About Drugs. Droxia slide 2 of 10, Droxia. Talk with your doctor about your specific risk. Clean the spill area using a detergent solution followed by clean water. A type of cancer called leukemia and skin cancer have happened in people taking this drug for a long time. Using hydroxyurea may increase your risk of developing other types of cancer, such as leukemia or skin cancer. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Hydrea is classified as an "antimetabolite. Medically reviewed by Drugs. Wash your hands with soap and water before and after Hyydrea touch the bottle or medication. See also: Hydrea dosage information in more detail. The pattern of serum enzyme elevations is typically mixed or cholestatic, but hepatocellular instances have also been reported. Before taking hydroxyurea, tell your doctor and pharmacist Hyerea you are Hydrra to hydroxyurea, any other medications, Hydreaa any of the inactive ingredients in hydroxyurea capsules or tablets. You may report Hyddrea effects to the FDA at These side effects are more likely to happen when you start treatment or when your doctor increases your dosage. AIDS ; F A type of cancer called leukemia and skin cancer have happened in people taking this drug for a long time. If hydroxyurea gets into your eyes, immediately flush your eyes with water for at least 15 minutes. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. Serious side effects and their symptoms can include the following:. It has not been linked to cases of chronic hepatitis or vanishing bile duct syndrome. Hydroxyurea can weaken your immune system. What should I know about storage and disposal of this medication? Do not take a double dose to make up for a missed one. Cancer ; FDA warnings This drug has black box warnings.
Hydrea - right! think This method of hydroxyurea synthesis was patented Hydrfa Hussain Hydrda al. This information is not a substitute for medical advice. They will check either the number of cancer cells in your body or the shape of your red blood cells. Avoid being near people who are sick or have infections. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Antimetabolites are cell-cycle specific. This may increase the risk that you will develop a serious infection Hyddrea bleeding. Hgdrea cells are progeny of a small pool of immature committed erythroid precursors BFU-e that retain Hydrea ability to produce HbF. The following are the types of chemotherapy:. Fever caused by hydroxyurea: a report of three cases and review of the literature. Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease. Skip to Content. Patient assistance may be available to qualifying individuals depending upon prescription drug coverage. Avoid exposure to sunlight or tanning beds. Hydroxyurea also increases the production of fetal hemoglobin, via an unknown mechanism of action, which increases overall hemoglobin levels and decreases sickling in patients with sickle cell anemia. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Your provider will monitor your kidney function with blood work. Classification: Antimetabolite. Ask your pharmacist for a list of the ingredients. Retrieved 8 December Swallow the capsules whole; do not split, chew, or crush them. This medicine will not cure sickle cell anemia. It is important for you to keep a written list of all of Hgdrea prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Tell your doctor Hdrea pharmacist about any medicines you are taking. Views Read Edit View history. Although these drugs are divided Hycrea groups, there is Hydea overlap among some of the specific drugs. Unless your doctor HHydrea Hydrea otherwise, continue your normal diet. You may not be able to become pregnant or father a child after treatment with this drug. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. However, it is important to use birth control because hydroxyurea may harm the baby if a pregnancy does occur. The hydroxyurea 1,mg tablets Siklos are scored so that they can easily be split into halves or quarters to provide smaller doses. Use the medicine exactly as directed. In other projects Wikimedia Commons. Am J Hematol ; Do not let anyone else take your medication. What should I know about storage and disposal of this medication? Not all side effects are listed above. Do not take a double dose to make up for the forgotten dose.
Hydrea is used to treat certain types of cancer (melanoma, chronic myelocytic leukemia, cancer of the ovary, and primary skin cancer of the head and neck) or sickled red blood cells. Active ingredient of this drug is hydroxyurea. The exact mechanism of its action is unknown, it is supposed that it is cell cycle specific for the S phase of cell division, it interfere with synthesis of DNA, with no effect on synthesis of RNA or protein.
Dosage and direction
Take this potent medication exactly as prescribed. Drink plenty of water during treatment to assist your kidney to remove the drug from the blood and diminish side effects. The medicine may be taken with or without food. You may be advised by your doctor to poor the content of Hydrea capsule into a glass of water, if so mix it throughly and drink whole immediately. Do not touch or inhale the drug powder from the capsule. Even if such symptoms as nausea or vomiting appear, do not stop taking this medication. Contact your doctor if you are immediately vomiting after the dose. This drug may increase the risk of sickness and inflammation due to its effect on amount of blood cells which control immunity.
Before to take Hydrea consult your doctor if you are being treated with radiation therapy or are currently on interferon (Actimmune, Betaseron, Roferon, Intron, Infergen, Alferon, Rebetron, Rebif). Notify your doctor about diseases you have and especially about poor bone marrow function, liver disease, or kidney disease.
Do not take Hydrea if you are allergic to the components of the drug. This medicine is contraindicated in the patients with bone marrow depression (leukopenia or thrombocytopenia). This medicine may be harmful to an unborn baby. Do not take Hydrea if you are pregnant or breastfeeding.
Possible side effect
Besides signs of allergic reaction such as facial swelling, skin rash and eruptions, hives, and pinpoint red spots on your skin Hydrea may cause skin ulcers, red patches, or darkened skin, symptoms of fever, flu, chills, white patches or sores inside your mouth or on your lips, body aches, nausea or vomiting, loss of appetite, diarrhea, easy bruising or bleeding, unusual weakness.
Do not start or stop treatment with any medication without your doctor's permission. Inform your health care advisor about all drugs, health products, vitamins, minerals, and supplement substances you are currently taking and especially about anti-cancer drugs, didanosine, stavudine, to treat gout.
Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.
Immediate medical help is needed if excessive amount of this drug was taken. Contact your doctor the soonest if somebody swallowed too much of Hydrea by chance or you suspect overdose. Symptoms of overdose are worsened side effects such as violet erythema, soreness, severe generalized hyperpigmentation of the skin, edema on palms and soles followed by scaling of hands and feet, and stomatitis.
Store Hydrea at room temperature between 20 and 25 C (68 and 77 F) away from moisture and heat.
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.