Call your doctor if your symptoms do not improve after using this medicine. How easy was it to take this drug? Related Imitrex.
Analogue-based Drug Discovery. Retrieved 3 March What is the most important information I should know about sumatriptan? Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazidlinezolidmethylene blue injection, phenelzinerasagilineselegilineor tranylcypromine. This Patient Information has been approved by the U. Antimigraine preparations N02C. Higher doses may have a greater risk of adverse reactions [see Clinical Studies 14 ]. Vasospastic coronary artery disease. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. Call your doctor if your symptoms do not improve after using this medicine. It has not been confirmed that sumatriptan is safe and effective for use in children. Do not use more than 40 milligrams of sumatriptan nasal spray or 44 milligrams of sumatriptan nosepiece capsules within 24 hours. What is sumatriptan? I took the pill and within 5 - 10 my entire right side of my body was not working, I had lost all straight. A prescription for this medication is refillable. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. The drug is generically available in U. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens [see Contraindications 4Warnings and Precautions 5. Daily news summary. Most of a radiolabeled dose of sumatriptan excreted in the urine is the major metabolite indole acetic acid IAA or the IAA glucuronide, both of which are inactive. This medicine may cause problems if you have heart disease. It appears to act in migraine by binding to selected receptors for serotonin found in the blood vessels 5HT1b and nerve endings 5HT1d. Imitrex side effects in more detail. Be sure that you discuss with your doctor the risks of using this medicine as well as the benefits that it can have. What is the most important information I should know about sumatriptan? If these effects occur, get emergency help at once. Use: For the acute treatment of migraine with or without aura. To help avoid interactions, your doctor should manage all of your medications carefully. Side effects are common with this form of sumatriptan only because of how rapidly the medication enters the system. When injected, sumatriptan is faster-acting usually within 10 minutesbut the effect lasts for a shorter time. Sumatriptan has been available in the United States since Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. How to tell if the drug is working: Your symptoms of migraine should get better. Never use more than your recommended dose. Retrieved 3 March Be sure that you discuss with your doctor the risks of using this medicine as well as the benefits that it can have. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers. Disclaimer: Our goal is to provide you with the most relevant and current information. Sumatriptan may be used as part of a combination therapy. It is very important that your doctor check your progress at regular visits. So I waited for a migraine to hit at home where my huband was around to bring me to the ER god Imitres I had a reaction. Copyright Cerner Multum, Inc. Check with your doctor right Imitrsx if you have chest discomfort, jaw or neck tightness after using this medicine. Keep this medication in the container it came in, tightly closed, and out of reach of children. Archived from the original on 17 February Rated Imitrex for Migraine Report Prescribed for migraines. Imitrex should not be used to treat a common tension headache or a headache that causes loss of movement on one side of your body. Very depressing. I took the pill and within 5 - 10 my entire right side of my body was not working, I had lost all straight. Events reported have included coronary artery vasospasmtransient myocardial ischemia, myocardial infarctionventricular tachycardiaand ventricular fibrillation V-Fib. Tips for Good Reviews Only rate drugs or treatments you've tried. I have looked up some of the triggers. Glaxo Group Ltd.
Imitrex - thank
Email Address. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Tell your doctor if you have any heart Imjtrex disorders. IImitrex most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. What happens if I overdose. The dose can Imotrex repeated after 2 hours. Inform patients that use of acute migraine drugs for 10 or more days per month may lead to an exacerbation of headache and encourage patients to record headache frequency and drug use e. Agonists: 2Cs e. Medicines and Healthcare Products Regulatory Agency. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers. Store it at room temperature, away from excess heat and moisture not in the bathroom. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Imitrex dosage information in more detail. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Imitrex only for the indication prescribed. For people with uncontrolled high blood pressure: Sumatriptan can increase your blood pressure. Patients with risk factors such as high cholesterol, diabetes or high blood pressure may need further testing before using triptans.
||Tell your doctor if you also use:. Ergot-containing drugs have Imitreex reported to cause prolonged vasospastic reactions. Browse Drugs and Medicines. It's vital Imiyrex ease in slowly Imitrex continue to…. I'm very thankful to my neurologist and the med for giving me relief. How to take sumatriptan. Scientists are working on new…. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Other uses for this medicine What special precautions should I follow. Patients who have cardiovascular, cerebrovascular or peripheral vascular disease affecting the blood vessels should not use this medication. Do not split the tablet. Some examples of ergot-type medicines are dihydroergotamine D. My last cluster knock wood has been about 5yrs ago, I went thru about injections. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Use this medicine only if your condition has been confirmed by a doctor as migraine headaches. Accordingly, the bioavailability of sumatriptan following oral administration may be markedly increased in patients with liver disease.
||A new rapid-release tablet formulation has Imiyrex same bioavailability, but the maximum concentration is achieved on average 10—15 minutes earlier. Read on to learn more about…. Amitriptyline Nortriptyline Imipramine. It is also effective in cluster headache as an abortive medication. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. Molecular Neurobiology. This medicine may cause a serious type of allergic reaction called anaphylaxis. Burroughs Mahlon Kline John K.
||Community Catalyst. Daily news summary. Advertising Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Where can I get more information. Antagonists: Agomelatine Imitrex antipsychotics e. Also, tell your doctor if you have sudden or severe abdominal or stomach pain or bloody diarrhea after using this medicine. I've taken these injections on and off over the last 10yrs, but the first time I took it, I was totally amazed how fast it started to work sec's and the headache was gone in min's. Dimetotiazine Dotarizine Iprazochrome Oxetorone Pizotifen.
||This is Imitrex a complete list of side effects and others may occur. Read and carefully follow any Instructions for Imotrex provided with your medicine. Spoke to my doctor who upped my dossage to 50 mg and I only need to take one. Anyways, I love this medication for making me feel back to myself again. This increases your risk of side effects.
NDC 1 2 3 In these cases, your doctor may want to change the dose, or other precautions may be necessary. You have a higher risk for heart disease if you:. Use only after a clear diagnosis of migraine has been established Oral: Initial dose: 25 mg, 50 mg, or mg orally, once -If some response to first dose occurs, a second dose may be administered at least 2 hours after first dose if needed -Oral doses of 50 and mg may provide greater relief than 25 mg; however, a mg dose may not provide greater effect than a 50 mg dose Maximum dose: mg per 24 hours Intranasal: Nasal spray: Initial dose: 5 mg, 10 mg, or 20 mg into one nostril, once -Administer the 5 and 20 mg doses as a single spray in 1 nostril; the 10 mg dose may be administered as 5 mg into each nostril -If some response to first dose occurs, a second dose may be administered at least 2 hours after first dose if needed Maximum dose: 40 mg per 24 hours Comments: -Treatment should be started at the first sign of a migraine headache, or associated symptoms such as nausea, vomiting, or photophobia; this drug should not be used for migraine prophylaxis. Heart attack and other heart problems. Read and carefully follow any Instructions for Use provided with your medicine.
Sumatriptan is a drug that is used for treating migraine attacks with or without the presence of an aura, to relieve cluster headache attacks. Sumatriptan is a Specific and selective agonist of 5-HT1-serotonin receptors localized mainly in blood vessels of the brain. Migraine headaches are believed to be stipulated by widening of blood vessels in the brain. Sumatriptan causes vasoconstriction of the carotid arterial bed which provides extracranial and intracranial tissues with blood without a significant impact on cerebral blood flow. It also inhibits activity of receptor which are responsible for transmission of pain signals by nerves to the brain.
Dosage and direction
Treatment with Sumatripan should be done just before the starting of a migraine attack. Recommended oral dose of adults is 25-50 mg, the dose maybe increased up to 100 mg if necessary. The medication is effective at any stage of the attack but if it does not help during the attack additional dose should not be taken. Treatment with Sumatriptan should be continued to prevent the next attack. Tablet of Sumatriptan should be swallowed whole, take it with a big glass of water. Usual intranasal dose of 5-20 mg may be increased to the maximum dose of 40 mg daily.
Sumatriptan is used only to treat an acute, classic migraine attack or a cluster headache, it should not be used for treatment of certain unusual types of migraine. Patients with uncontrolled high blood pressure should not use Sumatriptan.
Hypersensitivity, basal, ophtalmoplegic, hemiplegic forms of migraine, ischemic heart disease (including suspected it), angina (including angina Printsmetala), myocardial infarction (also in history), hypertension, peripheral arterial occlusive disease, stroke or transient cerebrovascular accident (also in history), liver and kidney failure. Cautiousness should be exercised in patients with epilepsy (including any condition with low epileptic threshold), hypertension, pregnancy, breastfeeding, in infants and adolescents (younger than 18 y.o.), in patients older than 65 y.o.; simultaneous intake of medications which contain ergotamine and its derivatives, MAO inhibitors, and also during the period of 14 days after their cancellation.
Possible side effect
This medication is usually well tolerated and adverse reactions are not expected. Most frequent side effects include pain or tightness in the chest or throat, tingling, flushing, weakness, dizziness, abdominal discomfort, sweating, nasal irritation, and injection site reactions. Allergic reactions as adverse reactions of organism to Sumatriptan are also possible.
Co-administration with ergotamine and medications containing ergotamin may develop a continued spasm of blood vessels (the interval between administration of these medications must be at least 24 h). Interaction of Sumatriptan and MAO inhibitors (isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane)) is also possible resulting in increased concentration of Sumatriptan. Concomitant use of Sumatriptan with selective serotonin reuptake inhibitors or SSRIs, including fluoxetine (Prozac), citalopram (Celexa), paroxetine (Paxil), and sertraline (Zoloft) or serotonin and norepinephrine reuptake inhibitors, including venlafaxine (Effexor), duloxetine (Cymbalta), and desvenlafaxine (Pristiq) may promote weakness, hyperreflexia and poor coordination of movements.
Sumatriptan is not meant for regular use, it is taken only during an attack.
Be especially attentive to such symptoms as bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor as they may be signs of Sumatriptan overdose. Inform your health care advisor immediately about your condition nor seek for emergency medical help.
Store this medication at a temperature of 2-30 C (36-86 F) in a tight container resistant to light and moisture.
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.