Nimotop - shall
Interaction with Grapefruit Juice: Published data indicate that through inhibition of Nimootp P, grapefruit juice can increase plasma levels and augment pharmacodynamic effects of Nomotop dihydropyridine calcium channel blockers. Numerous metabolites, all of which are either inactive or considerably less active than the parent compound, have been identified. Other reported clinical Nomotop has not identified differences in responses between the elderly and younger patients. In a monkey study simultaneous administration of the anti-HIV drug zidovudine i. New Zealand. This determination means that FDA will not begin procedures to withdraw approval of the abbreviated new drug applications ANDAs that refer to nimodipine capsules, 30 mg, and it will allow FDA to approve ANDAs that refer to this drug as long as they meet relevant legal and regulatory requirements. This is a complication that stems from a subarachnoid hemorrhage SAHwhich is bleeding in your brain. Patients taking enzyme-inducing anticonvulsants have lower plasma concentrations, while patients taking sodium valproate were markedly higher. The terminal elimination half-life is Ni,otop 8 to 9 Nimoto but earlier elimination rates are much more rapid, equivalent to a half-life of 1—2 hours; a consequence is the need for frequent every 4 hours dosing. After oral administration, it reaches Nmiotop plasma Nimtop within one and a half hours. This helps to prevent spasm in the blood vessels and reduces the risk of damage caused by insufficient blood flow to the brain after the bleeding. Number Analyzed. Weekly news roundup. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. People already diagnosed with cirrhosis are at an increased risk of serious side effects. This medication comes in a capsule form. In patients treated with enzyme inducing anticonvulsants such as phenytoin, phenobarbital and carbamazepine, the plasma concentrations of nimodipine may be markedly reduced. All rights reserved. Inadequate fluid intake, excessive sweating, diarrhea, or vomiting can lead to an excessive fall in blood pressure, too. Drug Class. Significant reduction of vascular reactivity with dantrolene and nimodipine in diabetic rats: a potential approach to cerebral vasospasm management in diabetes. S -Nimodipine CAS number: As a consequence, the blood pressure lowering effect may be increased. Capsules should be swallowed whole with a little liquid. Ion channel modulators. Consult a iNmotop or other health care professional for diagnosis and treatment of medical Nimotkp. Atorvastatin reduces cerebral vasospasm and infarction after Nimotol subarachnoid hemorrhage in elderly Chinese adults. A subarachnoid hemorrhage is usually the result of Nimotop
from a weakened area of the wall of a blood vessel, referred to as an aneurysm. Thus, concomitant intake of grapefruit juice and nimodipine can result in increased plasma concentrations and is not recommended. Nonmedicinal ingredients: gelatin, glycerin, peppermint oil, polyethylene glycol and titanium dioxide. Adverse events known to be associated with calcium channel blockers should be appropriately monitored. Nimotop Food Interactions Back to Top. Local News. She was treated with oral nimodipine. It may be necessary to adjust the dosage of nimodipine. Do not refrigerate. Latest News. Other Requirements Back to Top. Drug Information. Hepatic Dysfunction: The metabolism of nimodipine is decreased in patients with impaired hepatic function. Relevant information about this document from Regulations.
Nimotop is a nimodipine. It can prevent or eliminate spasm of vessels caused by various drugs such as serotonin or histamine. Due to its the high lipophility penetrates the blood-brain barrier (BBB). Nimotop improves stability and functional capacity of neurons. The medication also affects positively learning ability and memory by blocking of Ca2+-channels in certain brain areas, such as the hippocampus and cerebral cortex.
Dosage and direction
Take the medication orally exactly as prescribed to you. Do not exceed the recommended dose. Take on an empty stomach with a full glass of water one hour before or two hours after a meal. To get the most benefit of the drug take it regularly.
Cautiousness should be exercised in individuals with severe bradycardia, liver failure, mild or moderate hypotension, myocardial infarction associated with the failure of left ventricular, intracranial hypertension, generalized edema of the brain tissue. Avoid drinking of grapefruit juice while you ar eon Nimptop. When Nimptop is used with rifampicin effectiveness of the former can be reduced. Simultaneous adminitration of nimodipine with cimetidine or valproic acid may lead to increased concentrations of nimodipine in blood serum. Beta-blockers used together with Nimptop may cause considerable drop in blood pressure. Procainamide, quinidine used together with Nimptop may significantly increase the risk of elongation of the QT interval.
The medication should not be used in patients with hypersensitivity to the medication, severe hypotension, pregnant and breastfeeding women.
Possible side effect
In case of severe signs of allergy seek immediate medical care: skin rash, difficulty breathing, facial swelling, hives. Inform your doctor as soon as possible also if you experience fainting or severe dizziness, unusually fast or slow heartbeats, easy bruising or bleeding, unusual weakness, swelling in your legs or ankles.
Inform your doctor about all prescribed, over-the-counter medications, herbal products and food supplements you use. Combined use of nimodipine and Fluoxetine leads to increased concentrations of nimodipine in blood serum. Prolonged use of nimodipine with Nortriptyline results in a slight increase in serum levels of nimodipine. If phenobarbital, phenytoin or carbamazepine were used for a long time before nimodipine they may reduces its bioavailability.
If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose.
Symptoms of overdose which may need you to apply immediately for professional medical attention are: chest pain, dizziness, fainting, weakness, shortness of breath, an unusually fast or slow heartbeat, confusion, slurred speech, or coma.
Store in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.
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