For Plehal reasons, before you start taking cilostazol it lPetal important that your doctor knows:. Ask your doctor or pharmacist to answer any questions you may have. Pletal side effects in more detail. Do not take a double dose Plefal make up for the dose that you missed. Grapefruit and grapefruit juice may interact with Pletal PPletal lead to unwanted side effects. Common cilostazol side-effects these affect less than 1 in 10 people. Skip the missed dose if it is almost time for your next scheduled dose. Before taking cilostazol, tell your doctor and pharmacist if you are allergic to cilostazol, any other medications, or any of the ingredients in cilostazol. Daily news summary. You may need urgent medical attention or hospitalisation. Drug Status Rx. Tell your doctor if any of these symptoms are severe or do not go away: headache diarrhea dizziness heartburn nausea stomach pain muscle pain Some side effects can be serious. Do not take more or less of it or take it more often than prescribed by your doctor. Email Address. Headache Ask your pharmacist to recommend a suitable painkiller. Cilostazol is also used for secondary stroke prevention. Eligibility Criteria. Drug Information available for: Cilostazol. Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. Pletal Images. The proton pump inhibitor omeprazolea potent inhibitor of CYP2C19, increases exposure to the active metabolite of cilostazol. Take the container with you, even if it is empty. Pharmaceutical Benefits Scheme. Discuss the use of grapefruit products with your doctor. If you are not sure what to do, ask your doctor or pharmacist. Please check and try again Please enter recipient's email Recipient's email is invalid. Pletal is usually taken twice a day on an empty stomach, at least 30 minutes before or 2 hours after breakfast or dinner. Too many risks. If you forget to take it If it is less than 6 hours before your next dose, skip the dose you missed and take your next dose when you are meant to. Recommendation: Reject. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. From Wikipedia, the free encyclopedia. Download leaflet Reporting side effects Data sources Disclaimer What it is used for Pletal is indicated for the symptomatic improvement of intermittent claudication as indicated by increased maximal and pain-free walking distances in patients who do not have rest pain and who do not have evidence of peripheral tissue necrosis. Headache Ask your pharmacist to recommend a suitable painkiller. If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:. This medicine is available from a pharmacist and requires a prescription. Otsuka Australia Pharmaceutical Pty Ltd. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk. Cilostazol is used to treat intermittent claudication. There is a total of 5 error s on this form, details are below. Never take more than the prescribed dose. Brand names. Clinical Claim The submission claimed that cilostazol is statistically significantly superior to placebo for all primary and secondary endpoints but is associated with greater toxicity. Miscellaneous cardiovascular agents Platelet aggregation inhibitors. Do not leave it on a window sill or in the car. What it looks like 50 mg tablet not currently marketed. Available for Android and iOS devices. You can opt Pletal at any time or find out more by reading our cookie Plehal. This medicine helps to control your condition, but does not cure it. Retrieved Beraprost Iloprost Prostacyclin Treprostinil. Otsuka Pharmaceutical Co. By mouth tablets. In trials, the incidence and withdrawal of patients from treatment due to adverse effects was high. Plehal was approved for Plftal use in the United States in Headache Ask your pharmacist to recommend a suitable painkiller. It Pltal not take the place of talking to your doctor or pharmacist. Other uses for this medicine. For details see our conditions. Symptoms of an overdose may include:. Taking it at the same time each day will have the best effect. Drug Status Rx. Browse Drugs and Medicines. Pletal is used to treat the symptoms of intermittent claudication. Cilostazol is an antiplatelet agent indicated in patients with intermitent claudication to improve maximum and pain-free walking distance and time in peripheral arterial disease. This is consistent with the clinical claim in the previous submission, which was accepted by the PBAC. The proton pump inhibitor omeprazolea potent inhibitor of CYP2C19, increases exposure to the active metabolite of cilostazol. Take the container with you, even if it is empty. Follow the instructions they give you. It is important to keep taking your medicine even if you feel well. The PBAC did not comment on the requested restriction. Health Tools Feeling unwell? Take one tablet in the morning and one tablet in the evening. Cilostazol is dangerous for people with severe heart failure. Pletal Images. Monthly newsletter. Discuss the use of grapefruit products with your doctor. A single report has been made of grapefruit juice possibly increasing the effects of cilostazol;  some drug information sources list this as a possible interaction. See also: Pletal side effects in more detail. Looking to lose weight this year? If you do not understand the instructions on the box, ask your doctor or pharmacist for help. Skip to Content. Results of Trials The re-submission reaffirmed the claim that the treatment benefit with cilostazol is clinically relevant, and presented the following information to support this claim: Transformation of treadmill walking distances in all trials to real life flat-ground walking distances. About About Drugs.
Pletal - are If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist Plftal advice. Search Pleatl terms x. The Pletal noted the results of a systematic review and meta-analysis of drug therapy for IC Momsen et al which suggested that the highest benefit in terms of walking distance is obtained P,etal treating patients with lipid lowering agents. Discuss the use of grapefruit products with your doctor. The efficacy of statins has not been compared head-to head to cilostazol and the data quoted by the PBAC, which was not part of the submission, has not been fully reviewed or substantiated. Do not breast-feed if you are taking this medicine. This medicine may cause dizziness in some people. If you are not sure what to do, ask your doctor or pharmacist. FDA Resources. You should not breast-feed while using this medicine. Headache Ask your pharmacist to recommend a suitable painkiller. Take the missed dose as soon as you remember. Correlation of improvement in walking distances with improvement in QoL SF and WIQ outcomes An analysis of patient rated treatment success with cilostazol compared with placebo Expert opinion Prof Dawson This medicine improves your ability to walk longer distances without pain. Cilostazol works in two ways. A single report has been made of grapefruit juice possibly increasing the effects of cilostazol;  some drug information sources list this as a possible interaction. If it has expired or is damaged, return it to your pharmacist for disposal. Intermittent claudication IC is a common debilitating symptom of peripheral arterial obstructive disease. Other side effects not listed above may also occur in Plletal people. Estimated PBS Usage and Financial Implications The likely number of patients per year was estimated by the re-submission to be less than 10, in Year 5. Trending Articles. Get emergency medical help if you have signs of an allergic reaction : hives ; difficult breathing; swelling of your face, lips, tongue, or throat. Views Read Edit View history. Cilostazol sil-OS-tah-zol. Visual appearance white, round, flat-faced tablet debossed "OG30" on one side. Your doctor may do some tests blood test, clotting test, echocardiogram of the heart from time to time to make sure the medicine is working and to prevent unwanted side effects. The table below contains some of the most common ones associated with cilostazol. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Ask your doctor or pharmacist to answer any questions you may have. Clinical Trials Clinical trials The re-submission presented a revised meta-analysis of 11 randomised trials comparing cilostazol mg twice daily with placebo, compared with a meta-analysis of 10 randomised trials in the previous submission. Study Description. In case of overdose, call the poison control helpline at Cloricromen Ditazole Vorapaxar. It may affect your developing baby if you take it during pregnancy. If the headache continues, speak with your doctor. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It considers submissions in this context. Outcome Measures. Cilostazol has been studied in people without heart failure, without evidence of harm, but much more data would be needed to determine no risk exists. For details see our conditions. Search for terms x.
Pletal is a medication used for reducing attacks of intermittent claudication (pain, cramping, numbness, or weakness in the foot, hip, thigh, or buttocks) that may occur after walking. Pletal is a a phosphodiesterase type 3 inhibitor. It widens arteries that supply blood to the legs. It also decreases the ability of platelets to stick together.
Dosage and directions
Take is exactly as directed by your doctor. Take Pletal by mouth at least 30 minutes before or 2 hours after eating. Do not eat grapefruit or drink grapefruit juice while you take Pletal. The effects of Pletal are not immediate. Although you may experience the benefits of Pletal 2 to 4 weeks after beginning treatment, treatment for up to 12 weeks may be necessary before Pletal takes effect.
Discuss with your doctor if you are pregnant, planning to become pregnant, or are breast-feeding; if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; if you have allergies to medicines, foods, or other substances; if you have liver or kidney problems.
Do not use the medicine if you have allergy to any its component or heart failure.
Possible side effects
The most common side effects include: abnormal stools; back pain; bloating or swelling of ankles, feet, or hands; diarrhea; dizziness; feeling of a whirling motion; gas; headache; increased cough; indigestion; infection; muscle aches; nausea; runny nose; sore throat; stomach pain; swelling of the legs and feet.. Serious side effects are allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; fast or irregular heartbeat; pounding in the chest; unusual bruising or bleeding; vomiting material that looks like coffee grounds. Seek medical help if you have one of them.
The following medications can interact with Pletal:Certain medicines that act on the liver ketoconazole, erythromycin, diltiazem, omeprazole).
If you miss a dose of Pletal take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once. If more than one dose is missed, contact your health care provider or pharmacist.
Seek urgent medical help if you overdosed Pletal. Overdose symptoms are diarrhea; dizziness; fast or irregular heartbeat; fatigue; low blood pressure; severe headache; weakness.
Store Pletal between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container, away from heat, moisture, and light. Do not store in the bathroom. Keep Pletal out of the reach of children and away from pets.
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.