Certain drugs tend to produce hyperglycemia and may lead to loss of blood glucose control. You can also help maintain sugar levels with a positive lifestyle change by being more active, losing weight, stop smoking, limit your alcohol intake, and eating healthier. If you take Precose with insulin or other diabetes medications, your blood sugar could get too low. In addition, Precose diminishes the insulinotropic and weight-increasing effects of sulfonylureas. Therefore, treatment of these patients with Precose is not recommended. The dosage can be increased from 25 mg t. Aldodiose Glycolaldehyde. Placebo Plus Diet. Because of its mechanism of action, Precose when administered alone should not cause hypoglycemia in the fasted or postprandial state. In one study using Sprague-Dawley rats, acarbose was mixed with feed but carbohydrate deprivation was prevented by the addition of glucose to the diet. Aldose Ketose Furanose Pyranose. We comply with the HONcode standard for trustworthy health information - verify here. Approval History FDA approved However the maximum dose per day is mg. Caution with drugs that cause hyperglycemia eg, diuretics, steroids, estrogens, phenothiazines, thyroid products, phenytoin, niacin, sympathomimetics, calcium channel blockers, isoniazid.
Precose - sorry, that It is cheap and popular in China, but not in the U. Subscribe to Prwcose newsletters. Keep the bottle tightly closed when not in use. In diabetic patients, Precoxe short-term effect of these drug therapies is to decrease current blood glucose levels; the long-term Precpse is a reduction in HbA 1c level. Precoe for Android and iOS devices. Messages: 11, Likes Received: 6, Trophy Points: Aldotetroses Erythrose Threose Ketotetrose Prfcose. If you have Precse hypoglycemia and cannot eat or drink, use a glucagon injection. It is not known whether this drug is excreted in human milk. Precose should be taken three times daily at the start with the first bite of each main meal. In one study using Sprague-Dawley rats, acarbose was mixed with feed but carbohydrate deprivation was prevented by the addition of glucose to the diet. Serious side effects have been reported with Precose. It is a starch blocker, and inhibits alpha glucosidasean intestinal enzyme that releases glucose from larger carbohydrates. Because current information strongly suggests that abnormal blood glucose levels during pregnancy are associated with a higher incidence of congenital anomalies as well as increased neonatal morbidity and mortality, most experts recommend that insulin be used during pregnancy to maintain blood glucose levels as close to normal as possible. Aldose Ketose Furanose Pyranose. Precose has been shown to change the bioavailability of digoxin when they are coadministered, which may require digoxin dose adjustment. Did you experience many side effects while taking this drug. Plasma concentrations of Precose in renally impaired volunteers were proportionally increased relative to the degree of renal dysfunction. Follow the directions on your prescription label carefully. Unlike sulfonylureas or insulin, an overdose of Precose will not result in hypoglycemia. Colonic ulceration. There is no fixed dosage regimen for the management of diabetes mellitus with Precose or any other pharmacologic agent. Show Ignored Content. Forty-one of these 62 patients received treatment with mg t. Find support, ask questions and share your experiences. Small reductions in hematocrit occurred more often in Precose-treated patients than in placebo-treated patients but were not associated with reductions in hemoglobin. Six studies were performed in rats two strains, Sprague-Dawley and Wistar and two studies were performed in hamsters. Monitor serum transaminases every 3 months during 1 st year and periodically thereafter. In US studies including Precose doses up to the maximum approved dose of mg t. This action will prevent a sugar spike after Precos have a meal. No increased incidence of renal tumors was found in either of these Wistar rat studies. Take Prexose missed dose as soon as you Preclse be sure to Precosse it with a meal. Plus Diet 8. Following oral dosing of healthy volunteers with Precose C-labeled acarbose, peak plasma concentrations of radioactivity were attained 14—24 hours after dosing, while peak plasma concentrations of active drug were attained at approximately 1 hour. Monitor serum transaminases every 3 months during 1 st year and periodically thereafter. Gastrointestinal symptoms are the most common reactions to Precose. Stomach pain. The delayed absorption of acarbose-related radioactivity reflects the absorption of metabolites that may be formed by either intestinal bacteria or intestinal enzymatic hydrolysis. Chronic intestinal disease with marked disorders of digestion or absorption. Effects of acarbose addition on ruminal bacterial microbiota, lipopolysaccharide levels and fermentation characteristics in vitro. Because acarbose acts locally within the gastrointestinal tract, this low systemic bioavailability of parent compound is therapeutically desired. Who is this drug for? Lowest price near you. If hypoglycemia occurs, appropriate adjustments in the dosage of these agents should be made. It doesn't effect me that much. Subscribe to our newsletters. Because Precose prevents the breakdown of table sugar, patients should have a readily Precose source of glucose dextrose, D-glucose to treat symptoms of low blood sugar when taking Precose in combination with a sulfonylurea or insulin. Because of its mechanism of action, Precose when administered alone should not cause hypoglycemia in the fasted or postprandial state. Be sure your family and close friends know how to help you in an emergency. In one study using Sprague-Dawley rats, acarbose was mixed with feed but carbohydrate deprivation was prevented by the addition of glucose to the diet. This may be achieved by initiating treatment at 25 mg once per day and subsequently increasing the frequency of administration to achieve 25 mg t. Drug Status Rx. Other drugs may interact with acarbose, including prescription and over-the-counter medicines, vitaminsand herbal products. Following oral dosing of healthy volunteers with 14 C-labeled acarbose, peak plasma concentrations of radioactivity were attained 14—24 hours after dosing, while peak plasma concentrations of active drug were attained at approximately 1 hour. About About Drugs. How likely would you be to recommend Precose to a friend? This is not a complete list of Precose drug interactions. Contraindications: Ketoacidosis. Precose Drug Class Back to Top. Especially tell your doctor if you take: other medications for diabetes digoxin Lanoxin diuretics 'water pills' estrogens isoniazid medications for high blood pressure or colds oral contraceptives pancreatic enzymes phenytoin Dilantin steroids thyroid medications vitamins This is not a complete list of Precose drug interactions. The recommended starting dosage of Precose is 25 mg given orally three times daily at the start with the first bite of each main meal. Precose is also contraindicated Precose Preocse with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction or in patients predisposed to intestinal obstruction. Common side effects of Precose include Prwcose pain, diarrhea, and flatulence. Intestinal adsorbents for example, charcoal and digestive enzyme preparations containing Prceose enzymes for example, amylase, pancreatin may reduce the effect of Precose and should not be taken concomitantly. Available for Android and iOS devices. Each tablet strength is white to yellow-tinged in color. Because current information strongly suggests that abnormal blood glucose levels during pregnancy are associated with a higher incidence of congenital anomalies as well as increased neonatal morbidity and mortality, most experts recommend that insulin be used during pregnancy to maintain blood glucose levels as close to normal as possible. Precose is available in bottles of and 50 mg strength in unit dose packages of It is a starch blocker, and inhibits alpha glucosidasean intestinal enzyme that releases glucose from larger carbohydrates. Acarbose treatment resulted in a significant increase in the incidence of renal tumors adenomas and adenocarcinomas and benign Leydig cell tumors. View All. Who is this drug for? In long-term studies up to 12 months, and including Precose doses up to mg t. The mean steady-state area under the curve AUC and maximum concentrations of acarbose were approximately 1. Everything I read stated that my energy should go up, but that wasn't the case with me. Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Excessive gas.
Acarbose slows the digestion of carbohydrates in the body, which helps control blood sugar levels.
Acarbose is used to treat type 2 diabetes. Acarbose is sometimes used in combination with insulin or other diabetes medications you take by mouth.
Dosage and direction
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
Take Acarbose with the first bite of a main meal, unless your doctor tells you otherwise.
Your medication needs may change if you become sick or injured, if you have a serious infection, or if you have any type of surgery. Your doctor may want you to stop taking acarbose for a short time if any of these situations affect you. Do not change your dose or stop taking acarbose without first talking to your doctor
Take care to keep your blood sugar from getting too low, causing hypoglycemia. You may have hypoglycemia if you skip a meal, exercise too long, drink alcohol, or are under stress.
Know the signs of low blood sugar (hypoglycemia) and how to recognize them:
hunger, weakness, nausea, irritability, tremors;
drowsiness, dizziness, headache, blurred vision;
confusion, trouble concentrating;
sweating, fast heartbeat;
seizure (convulsions); or
fainting, coma (severe hypoglycemia can be fatal).
Keep a supply of oral glucose (dextrose) with you in case you have low blood sugar. While you are taking acarbose, candy or table sugar (sucrose) may not work as well as dextrose in quickly raising your blood sugar. Also be sure your family and close friends know how to help you in an emergency.
Acarbose is only part of a complete program of treatment that also includes diet, exercise, and weight control. It is important to use this medicine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Avoid drinking alcohol while taking acarbose. Alcohol lowers blood sugar and may increase the risk of hypoglycemia.
Avoid taking a digestive enzyme such as pancreatin, amylase, or lipase at the same time you take acarbose. These enzymes can make it harder for your body to absorb acarbose. Products that contain digestive enzymes include Arco-Lase, Cotazym, Donnazyme, Pancrease, Creon, and Ku-Zyme.
Possible side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these liver symptoms:
nausea, stomach pain, loss of appetite;
dark urine, clay-colored stools; or
jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
mild stomach pain, gas, bloating;
mild skin rash or itching.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
You may be more likely to have hyperglycemia (high blood sugar) if you are taking acarbose with other drugs that raise blood sugar. Drugs that can raise blood sugar include:
niacin, nicotine patches or gum;
diuretics (water pills);
steroids (prednisone and others);
phenothiazines (Compazine and others);
thyroid medicine (Synthroid and others);
birth control pills and other hormones;
seizure medications (Dilantin and others);
cold or asthma medications;
diet pills, stimulants, or medicines to treat ADHD; or
a calcium channel blocker such as diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nifedipine (Procardia, Adalat), verapamil (Calan, Covera, Isoptin, Verelan), and others.
This list is not complete and there may be other drugs that can affect your blood sugar or interact with acarbose. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Take the missed dose as soon as you remember (be sure to take it with a meal). If it has been longer than 15 minutes since you started your meal, you may still take acarbose but it may be less effective than taking it with the first bite of the meal. Do not take acarbose between meals, and do not take extra medicine to make up a missed dose.
Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include bloating, gas, or stomach discomfort.
In case of overdose, do not eat or drink anything containing carbohydrates for the next 4 to 6 hours.
Store Acarbose at room temperature in a tightly closed container, away from moisture and heat
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.